Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

Garcia-Bermudez J, Baudrier L, La K, Zhu XG, Fidelin J, Sviderskiy VO, Papagiannakopoulos T, Molina H, Snuderl M, Lewis CA, Possemato RL, Birsoy K.

Nature cell biology. 2018; 20(7):775-781. NIHMSID: NIHMS966847. PubMed [journal]PMID: 29941933 PMCID: PMC6030478

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Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

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Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice