Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice

Petersen DR, Saba LM, Sayin VI, Papagiannakopoulos T, Schmidt EE, Merrill GF, Orlicky DJ, Shearn CT.

PloS one. 2018; 13(5):e0198139. PubMed [journal]PMID: 29799837 PMCID: PMC5969769

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Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

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Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs