SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity

Zhong H, Lu W, Tang Y, Wiel C, Wei Y, Cao J, Riedlinger G, Papagiannakopoulos T, Guo JY, Bergo MO, Kang Y, Ganesan S, Sabaawy HE, Pine SR.

Oncogene. 2023 Jun;42(27):2183-2194. doi: 10.1038/s41388-023-02715-5. Epub 2023 May 31. PMID: 37258742

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Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

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Metabolic Reprogramming by Histone Deacetylase Inhibition Selectively Targets NRF2-activated tumors